9V8L image
Deposition Date 2025-05-29
Release Date 2026-06-10
Last Version Date 2026-06-10
Entry Detail
PDB ID:
9V8L
Keywords:
GENE REGULATION
Title:
Cryo-EM structure of the cPRC1-di-nucleosome (loose) complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
6.60 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9V8L validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H3.1
Gene (Uniprot):H3C1, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3C10, H3C11, H3C12
Chain IDs:A, C (auth: E), M (auth: K), O
Chain Length:136
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P68431 Pfam ID:PF00125
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H4
Gene (Uniprot):H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16
Chain IDs:G (auth: B), H (auth: F), S, T
Chain Length:103
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P62805 Pfam ID:PF15511
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H2B type 1-C/E/F/G/I
Gene (Uniprot):H2BC4, H2BC6, H2BC7, H2BC8, H2BC10
Chain IDs:D, F (auth: H), P, R
Chain Length:126
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P62807 Pfam ID:PF00125
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1-H
Gene (Uniprot):H2AC12
Chain IDs:B (auth: G), E (auth: C), N (auth: L), Q
Chain Length:128
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:Q96KK5 Pfam ID:PF00125, PF16211
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (271-MER)
Chain IDs:I
Chain Length:271
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (271-MER)
Chain IDs:J
Chain Length:271
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Polycomb complex protein BMI-
Gene (Uniprot):BMI1
Chain IDs:K (auth: M)
Chain Length:326
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P35226 Pfam ID:PF13923, PF16207
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:E3 ubiquitin-protein ligase R
Gene (Uniprot):RNF2
Chain IDs:L (auth: N)
Chain Length:336
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q99496 Pfam ID:PF13923, PF16207 EC:2.3.2.27
Ligand Molecules
ZN
Primary Citation
Structural mechanisms of PRC1-mediated interplay between gene repression and activation
To Be Published ? ? ? (?)
Primary Citation of related structures
9V8L
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