9UVY image
Deposition Date 2025-05-11
Release Date 2026-05-06
Last Version Date 2026-05-06
Entry Detail
PDB ID:
9UVY
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of Vasopressin receptor 2 (V2R)-ARK1 with tolvaptan
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.98 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9UVY validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Vasopressin V2 receptor,ARK1
Gene (Uniprot):AVPR2
Chain IDs:A
Chain Length:765
Number of Molecules:1
Biological Source:Homo sapiens, synthetic construct
UniProt ID:P30518 Pfam ID:PF00001
Ligand Molecules
A1IT8
Primary Citation
A Rapid and Universal Pipeline for High-Resolution GPCR Structure Determination through <em>In Silico</em> Construct Optimization and de novo Protein Design
Biorxiv ? ? ? (2026)
DOI: 10.64898/2026.04.02.716066
Primary Citation of related structures
9UVY
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