ISDA: 9UVL

Deposition Date 2025-05-10

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9UVL

Keywords:

CELL INVASION

Title:

Crystal structure of AGAP1-GDP complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia phage ecszw_1

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.49 Å

R-Value Free:

0.26

R-Value Work:

0.21

R-Value Observed:

0.22

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Arf-GAP with GTPase, ANK repe
Gene (Uniprot):AGAP1
Chain IDs:A, B, C, D, E, F, G, H
Chain Length:172
Number of Molecules:8
Biological Source:Homo sapiens

UniProt ID:Q9UPQ3 Pfam ID:PF00071

Ligand Molecules

GDP

Primary Citation

AGAP1 and its noncanonical GDP binding regulate triple-negative breast cancer carcinogenesis

Zhang, S, Zhang, Y, Cheng, N, Wang, H, Zhuo, Z, Huang, H, Deng, X, Li, Z, Meng, G, Zhang, H.Show

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Primary Citation of related structures

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