ISDA: 9USA

Deposition Date 2025-05-01

Release Date 2026-04-01

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9USA

Keywords:

OXIDOREDUCTASE

Title:

Whole structure of C44S/C47S double mutant form of human prostamide/prostaglandin F synthase (PGFS)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.30 Å

R-Value Free:

0.24

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 31 2 1

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Prostamide/prostaglandin F sy
Mutagens:C44S, C47S
Chain IDs:A
Chain Length:198
Number of Molecules:1
Biological Source:Homo sapiens

Primary Citation

Structural and Biophysical Analyses of Human Prostamide/Prostaglandin F Synthase with Two Active Form-Mimicking Mutations.

Cheon, S.W, Nguyen, Y.T.K, Kang, J.M, Yu, Y, Heo, Y, Kim, H.S, Han, B.W.Show

Biomolecules 16 ? ? (2026)

PMID: 41750332 DOI: 10.3390/biom16020262

Primary Citation of related structures

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