9UPY image
Deposition Date 2025-04-29
Release Date 2026-09-23
Last Version Date 2026-09-23
Entry Detail
PDB ID:
9UPY
Title:
Cryo-EM structure of the ZQ16-bound GPR84 receptor-Gi complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.10 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Chain IDs:B (auth: A)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:C (auth: B)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:D (auth: G)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:G-protein coupled receptor 84
Gene (Uniprot):GPR84
Chain IDs:A (auth: R)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Pharmacological modulation of GPR84 revealed by dual states structures and immune functional assays.
Exp.Mol.Med. ? ? ? (2026)
PMID: 42722702 DOI: 10.1038/s12276-026-01841-w
Primary Citation of related structures
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