9UPR image
Deposition Date 2025-04-28
Release Date 2026-05-06
Last Version Date 2026-05-06
Entry Detail
PDB ID:
9UPR
Keywords:
VIRAL PROTEIN
Title:
Cryo-EM structure of the N-terminal domain of Omicron BA.1 in complex with nanobody N103 and S2L20 Fab
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Vicugna pacos (Taxon ID: 30538)
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.77 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9UPR validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:S2L20 light chain
Chain IDs:A
Chain Length:236
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:9UPR
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:S2L20 heavy chain
Chain IDs:B
Chain Length:473
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:9UPR
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:nanobody N103
Chain IDs:C (auth: E)
Chain Length:122
Number of Molecules:1
Biological Source:Vicugna pacos
UniProt ID:9UPR
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Spike glycoprotein
Gene (Uniprot):S
Chain IDs:D (auth: F)
Chain Length:306
Number of Molecules:1
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTC2 Pfam ID:PF16451
Ligand Molecules
NAG
Primary Citation
Enhanced potency of an IgM-like nanobody targeting conserved epitope in SARS-CoV-2 spike N-terminal domain.
To Be Published ? ? ? (?)
Primary Citation of related structures
9UPR
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