ISDA: 9UMF

Deposition Date 2025-04-21

Release Date 2026-04-29

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9UMF

Keywords:

DNA BINDING PROTEIN/DNA

Title:

Human poly ADP-ribose polymerase(PARP-1 )zinc finger 1 bound to 17bp DNA

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.50 Å

R-Value Free:

0.23

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Poly [ADP-ribose] polymerase
Gene (Uniprot):PARP1
Chain IDs:A, B
Chain Length:87
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P09874 Pfam ID:PF00645 EC:2.4.2.30

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*GP*AP*GP*AP*AP*CP*
Chain IDs:C
Chain Length:17
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*GP*AP*GP*AP*TP*TP*
Chain IDs:D
Chain Length:17
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Human poly ADP-ribose polymerase(PARP-1 )zinc finger 1 bound to 17bp DNA of promoter of DR5

Yan, M, Zhang, H.Show

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Primary Citation of related structures

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