9UE8 image
Deposition Date 2025-04-08
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9UE8
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Crystal structure of MPXV A35R in complex with a neutralizing antibody BA345
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Monkeypox virus (Taxon ID: 10244)
Expression System(s):
Homo sapiens, Spodoptera frugiperda
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.20 Å
R-Value Free:
0.26
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 2 21 21
9UE8 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:345 Heavy Chain
Chain IDs:A, E, I, M, Q, U
Chain Length:221
Number of Molecules:6
Biological Source:Homo sapiens
UniProt ID:9UE8
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:345 Light Chain
Chain IDs:B, F, J, N, R, V
Chain Length:215
Number of Molecules:6
Biological Source:Homo sapiens
UniProt ID:9UE8
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Protein OPG161
Gene (Uniprot):OPG161
Chain IDs:C, D, G, H, K, L, O, P, S, T, W, X
Chain Length:152
Number of Molecules:12
Biological Source:Monkeypox virus
UniProt ID:A0A7H0DND2 Pfam ID:PF05966
Ligand Molecules
NA
Primary Citation
Human Broad-Spectrum Neutralizing Antibodies Reveal Therapeutic Potential Against Monkeypox and Orthopoxviruses
To be published ? ? ? (?)
Primary Citation of related structures
9UE8
Feedback Form
Name
Email
Institute
Feedback