9UE2 image
Deposition Date 2025-04-07
Release Date 2025-12-31
Last Version Date 2026-07-15
Entry Detail
PDB ID:
9UE2
Keywords:
TRANSFERASE
Title:
Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Lys181Ser/Trp185Gly/His280Ala with (S)-2-fluoro-3-(4-(trifluoromethyl)phenyl)propanoic acid
Biological Source:
Source Organism(s):
Rhodopseudomonas palustris CGA009 (Taxon ID: 258594)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.38 Å
R-Value Free:
0.17
R-Value Work:
0.16
R-Value Observed:
0.16
Space Group:
P 1 21 1
9UE2 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Fluoroacetate dehalogenase
Gene (Uniprot):RPA1163
Mutagens:K181S,W185G,H280A
Chain IDs:A, B
Chain Length:302
Number of Molecules:2
Biological Source:Rhodopseudomonas palustris CGA009
UniProt ID:Q6NAM1 Pfam ID:PF00561 EC:3.8.1.3
Ligand Molecules
A1ES3
Primary Citation
Creating highly active fluoroacetate dehalogenases via gate-based synergetic chain design.
Nat Commun 17 ? ? (2026)
PMID: 42062289 DOI: 10.1038/s41467-026-72741-w
Primary Citation of related structures
9UE2
Feedback Form
Name
Email
Institute
Feedback