9UE0 image
Deposition Date 2025-04-07
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9UE0
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Crystal structure of MPXV A35R in complex with a neutralizing antibody MA49
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Monkeypox virus (Taxon ID: 10244)
Expression System(s):
Homo sapiens, Spodoptera frugiperda
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.70 Å
R-Value Free:
0.26
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 21 21 21
9UE0 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Heavy Chain
Chain IDs:A
Chain Length:223
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:9UE0
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Light Chain
Chain IDs:B
Chain Length:214
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:9UE0
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Protein OPG161
Gene (Uniprot):OPG161
Chain IDs:C, D
Chain Length:124
Number of Molecules:2
Biological Source:Monkeypox virus
UniProt ID:A0A7H0DND2 Pfam ID:PF05966
Primary Citation
Human Broad-Spectrum Neutralizing Antibodies Reveal Therapeutic Potential Against Monkeypox and Orthopoxviruses
To be published ? ? ? (?)
Primary Citation of related structures
9UE0
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