9UDQ image
Deposition Date 2025-04-07
Release Date 2026-04-15
Last Version Date 2026-04-15
Entry Detail
PDB ID:
9UDQ
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Crystal structure of MPXV A35R in complex with a neutralizing antibody MA42
Biological Source:
Source Organism(s):
Monkeypox virus (Taxon ID: 10244)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda, Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.82 Å
R-Value Free:
0.27
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 21 21 2
9UDQ validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Light Chain
Chain IDs:B (auth: A), E (auth: C)
Chain Length:215
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Heavy Chain
Chain IDs:C (auth: F), F (auth: I)
Chain Length:236
Number of Molecules:2
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Protein OPG161
Gene (Uniprot):OPG161
Chain IDs:A (auth: J), D (auth: B)
Chain Length:124
Number of Molecules:2
Biological Source:Monkeypox virus
UniProt ID:A0A7H0DND2 Pfam ID:PF05966
Ligand Molecules
NA
Primary Citation
Human Broad-Spectrum Neutralizing Antibodies Reveal Therapeutic Potential Against Monkeypox and Orthopoxviruses
To be published ? ? ? (?)
Primary Citation of related structures
9UDQ
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