9U96 image
Deposition Date 2025-03-27
Release Date 2026-02-04
Last Version Date 2026-08-19
Entry Detail
PDB ID:
9U96
Keywords:
VIRAL PROTEIN
Title:
SARS-CoV2 Main protease(Mpro) complexed with TAB1 peptide
Biological Source:
Source Organism(s):
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.43 Å
R-Value Free:
0.24
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
C 1 2 1
9U96 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:3C-like proteinase nsp5
Gene (Uniprot):rep
Chain IDs:A, B
Chain Length:304
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTD1 Pfam ID:PF05409 EC:2.7.7.48
Polymer Type:polypeptide(L)
Molecule:LEU-THR-LEU-GLN-SER
Chain IDs:C, D
Chain Length:5
Number of Molecules:2
Biological Source:Homo sapiens
Ligand Molecules
NA
Primary Citation
The seven human coronavirus main proteases exhibit differential modulation of NF-kappa B suppression via TAB1 cleavage.
Commun Biol ? ? ? (2026)
PMID: 42168570 DOI: 10.1038/s42003-026-10225-9
Primary Citation of related structures
9U96
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