9U5E image
Deposition Date 2025-03-21
Release Date 2026-10-07
Last Version Date 2026-10-07
Entry Detail
PDB ID:
9U5E
Keywords:
MEMBRANE PROTEIN
Title:
cryo-EM structure of l-SPD bound D1R-Gs complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Lama glama (Taxon ID: 9844)
Expression System(s):
Spodoptera frugiperda, Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.49 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9U5E validation report missing
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAS, GNAS
Chain IDs:A
Chain Length:245
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P63092,Q5JWF2 Pfam ID:PF00503 EC:3.6.5.-
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:345
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62873 Pfam ID:PF25391
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C (auth: G)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P59768 Pfam ID:PF00631
Polymer Type:polypeptide(L)
Molecule:Nanobody35
Chain IDs:D (auth: N)
Chain Length:139
Number of Molecules:1
Biological Source:Lama glama
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:D(1A) dopamine receptor
Gene (Uniprot):DRD1
Chain IDs:E (auth: R)
Chain Length:446
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P21728 Pfam ID:PF00001
Ligand Molecules
A1EN9
Primary Citation
cryo-EM structure of l-SPD binding to D2R
To Be Published ? ? ? (?)
Primary Citation of related structures
9U5E
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