9U43 image
Deposition Date 2025-03-19
Release Date 2026-09-23
Last Version Date 2026-09-23
Entry Detail
PDB ID:
9U43
Keywords:
SIGNALING PROTEIN/IMMUNE SYSTEM
Title:
Cryo-EM structure of D-peptide-GPCR-Gq complex
Biological Source:
Source Organism(s):
Clostridium perfringens (Taxon ID: 1502)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Trichoplusia ni, Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.02 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9U43 validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:C (auth: A)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:D (auth: B)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62873 Pfam ID:PF25391
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:E (auth: G)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P59768 Pfam ID:PF00631
Polymer Type:polypeptide(L)
Molecule:Nanobody 35
Chain IDs:F (auth: N)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Arg-vasopressin
Gene (Uniprot):AVP
Chain IDs:B (auth: P)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P01185 Pfam ID:PF00220
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:exo-alpha-sialidase,Vasopress
Gene (Uniprot):AVPR1A, nanH
Mutagens:D112K
Chain IDs:A (auth: R)
Chain Length:0
Number of Molecules:1
Biological Source:Clostridium perfringens, Homo sapiens
UniProt ID:Q59310,P37288 Pfam ID:PF00001 EC:3.2.1.18
Ligand Molecules
NA
Primary Citation
Cryo-EM structure of D-peptide-GPCR-Gq complex
To Be Published ? ? ? (?)
Primary Citation of related structures
9U43
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