ISDA: 9TZM

Deposition Date 2026-01-23

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9TZM

Keywords:

IMMUNE SYSTEM

Title:

Programmed cell death 1 ligand 1 with small molecule inhibitor ligand

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.90 Å

R-Value Free:

0.28

R-Value Work:

0.21

Space Group:

P 31 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Programmed cell death 1 ligan
Gene (Uniprot):CD274
Chain IDs:A, B
Chain Length:117
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9NZQ7 Pfam ID:PF07686

Ligand Molecules

A1JYC

Primary Citation

Novel Selenium-Containing Small Molecule PD-L1 Inhibitors: Design, Synthesis, and Evaluation of the Antitumor Activity.

Wang, J, Yu, S, Qian, L, Plewka, J, Ni, R, Wang, C, Zhang, F, Chen, Z, Awadasseid, A, Wu, Y, Magiera-Mularz, K, Zhang, W.Show

J.Med.Chem. ? ? ? (2026)

PMID: 42394434 DOI: 10.1021/acs.jmedchem.6c00363

Primary Citation of related structures

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