ISDA: 9TZ2

Deposition Date 2026-01-21

Release Date 2026-08-19

Last Version Date 2026-09-02

Entry Detail

PDB ID:

9TZ2

Keywords:

OXIDOREDUCTASE

Title:

human formylglycine-generating enzyme FGE, with surface loop and active site Cu(I)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Trichoplusia ni

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.15 Å

R-Value Free:

0.17

R-Value Work:

0.15

R-Value Observed:

0.15

Space Group:

P 21 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Formylglycine-generating enzy
Gene (Uniprot):SUMF1
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8NBK3 Pfam ID:PF03781 EC:1.8.3.7

Ligand Molecules

CU1

GOL

OXY

Primary Citation

New Structures of Human Formylglycine-generating Enzyme Reveal Features Important for Catalysis, Disease and Structure-based Drug Design.

Kowal, J.L, Alam, S, Radhakrishnan, K, Dickmanns, A, Neumann, P, Schlotawa, L, Ficner, R, Dierks, T, Rudolph, M.G, Niemann, H.H.Show

J.Mol.Biol. 438 169987 169987 (2026)

PMID: 42580400 DOI: 10.1016/j.jmb.2026.169987

Primary Citation of related structures

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