9TWT image
Deposition Date 2026-01-15
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
9TWT
Title:
Complex of E. coli leucyl-tRNA synthetase AN3365-resistant mutant D251N bound to tRNA(leu) and AN3365
Biological Source:
Source Organism(s):
Escherichia coli (Taxon ID: 562)
Method Details:
Experimental Method:
Resolution:
2.30 Å
R-Value Free:
0.25
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 1 21 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Leucine--tRNA ligase
Mutagens:D251N
Chain IDs:A
Chain Length:880
Number of Molecules:1
Biological Source:Escherichia coli
Polymer Type:polyribonucleotide
Molecule:tRNA(leu)
Chain IDs:B
Chain Length:86
Number of Molecules:1
Biological Source:Escherichia coli
Primary Citation
Mechanisms of Resistance to an Antibiotic Targeting Bacterial Leucyl-tRNA Synthetase
Nat Commun ? ? ? (2026)
Primary Citation of related structures
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