ISDA: 9TTA

Deposition Date 2026-01-06

Release Date 2026-05-06

Last Version Date 2026-05-06

Entry Detail

PDB ID:

9TTA

Keywords:

HYDROLASE

Title:

Crystal Structure of S12 bound to Ck2a

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.91 Å

R-Value Free:

0.28

R-Value Work:

0.22

R-Value Observed:

0.23

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Casein kinase II subunit alph
Gene (Uniprot):CSNK2A1
Chain IDs:A
Chain Length:328
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P68400 Pfam ID:PF00069 EC:2.7.11.1

Ligand Molecules

A1JXM

ACT

Primary Citation

Towards the Targeted Protein Degradation of CK2: Design and Synthesis of CAM4066-Based PROTACs

Day-Riley, S, Krajcovicov, S, Brear, P, Raj Sokha, A, Venne, J, Hyvonen, M, Whitehurst, B, Spring, D.R.Show

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Primary Citation of related structures

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