ISDA: 9TSN

Deposition Date 2025-12-30

Release Date 2026-05-13

Last Version Date 2026-05-13

Entry Detail

PDB ID:

9TSN

Keywords:

UNKNOWN FUNCTION

Title:

ProteinMPNN mutated KREP domain of PF3D7_1343700 (PfK13-KREP, 59,4% sequence identity)

Biological Source:

Source Organism(s):

Plasmodium falciparum 3D7 (Taxon ID: 36329)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.15 Å

R-Value Free:

0.22

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 31

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Kelch protein
Gene (Uniprot):PF13_0238
Chain IDs:A, B, C
Chain Length:306
Number of Molecules:3
Biological Source:Plasmodium falciparum 3D7

UniProt ID:A0A077LQB4

Ligand Molecules

BU3

EDO

TRS

Primary Citation

Stabilizing Plasmodium falciparum proteins for small molecule drug discovery.

Amann, M, Strasser, T, Einsle, O, Gunther, S.Show

Protein Sci. 35 e70614 e70614 (2026)

PMID: 42068230 DOI: 10.1002/pro.70614

Primary Citation of related structures

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