9TRU image
Deposition Date 2025-12-27
Release Date 2026-09-23
Last Version Date 2026-09-23
Entry Detail
PDB ID:
9TRU
Keywords:
HYDROLASE
Title:
Zebrafish dUTPase in complex with staphylococcal Stl repressor
Biological Source:
Source Organism(s):
Danio rerio (Taxon ID: 7955)
Staphylococcus aureus (Taxon ID: 1280)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.26 Å
R-Value Free:
0.26
R-Value Work:
0.22
R-Value Observed:
0.22
Space Group:
P 1 21 1
9TRU validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Deoxyuridine 5'-triphosphate
Gene (Uniprot):dut
Chain IDs:A, B, C, D, E, F
Chain Length:186
Number of Molecules:6
Biological Source:Danio rerio
UniProt ID:Q5XJ23 Pfam ID:PF00692 EC:3.6.1.23
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Orf20
Chain IDs:G, H (auth: I), I (auth: J), J (auth: H), K (auth: L), L (auth: K)
Chain Length:156
Number of Molecules:6
Biological Source:Staphylococcus aureus
UniProt ID:Q9F0J8
Ligand Molecules
MG
Primary Citation
A bacterial protein inhibitor of dUTPase disrupts zebrafish embryogenesis through a conserved active-site mechanism.
Protein Sci. 35 e70767 e70767 (2026)
PMID: 42747148 DOI: 10.1002/pro.70767
Primary Citation of related structures
7DLV
8C8I
8P8O
Feedback Form
Name
Email
Institute
Feedback