ISDA: 9TRD

Deposition Date 2025-12-23

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

9TRD

Keywords:

ANTIVIRAL PROTEIN

Title:

Bacterial antiviral defense protein PD-T7-3 (H122A) in complex with single-stranded DNA and a fragment of RNA

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.38 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Bacterial antiviral defense p
Chain IDs:A, B, C, E (auth: D), F (auth: E), G (auth: F), I (auth: G), J (auth: H), K (auth: I), M (auth: J), N (auth: K), O (auth: L)
Chain Length:0
Number of Molecules:12
Biological Source:Escherichia coli

Polymer Type:polyribonucleotide
Molecule:RNA
Chain IDs:Q (auth: M)
Chain Length:0
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polyribonucleotide
Molecule:RNA
Chain IDs:R (auth: N)
Chain Length:0
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:single-stranded DNA
Chain IDs:D (auth: S), H (auth: T), L (auth: U), P (auth: V)
Chain Length:0
Number of Molecules:4
Biological Source:synthetic construct

Ligand Molecules

Primary Citation

Standalone anti-phage HEPN nuclease PD-T7-3 is activated by ssDNA for tRNA cleavage

Puteikiene, R, Vassallo, C.N, Silanskas, A, Songailiene, I, Juozapaitis, J, Laub, M.T, Sasnauskas, G.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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