ISDA: 9TNI

Deposition Date 2025-12-15

Release Date 2026-10-21

Last Version Date 2026-10-21

Entry Detail

PDB ID:

9TNI

Keywords:

TRANSFERASE

Title:

Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with inhibitor

Biological Source:

Source Organism(s):

Mycobacteroides abscessus ATCC 19977 (Taxon ID: 561007)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.59 Å

R-Value Free:

0.23

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

C 2 2 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Phosphopantetheine adenylyltr
Gene (Uniprot):coaD
Chain IDs:A, B, C
Chain Length:162
Number of Molecules:3
Biological Source:Mycobacteroides abscessus ATCC 19977

UniProt ID:B1MDL6 EC:2.7.7.3

Ligand Molecules

A1JW4

Primary Citation

Targeting Phosphopantetheine adenylyltransferase from Mycobacterium abscessus by divergent fragment elaboration strategies

Thomas, S.E, McCarthy, W, Coyne, A.G, Floto, R.A.Show

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Primary Citation of related structures

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