ISDA: 9TNG

Deposition Date 2025-12-15

Release Date 2026-05-13

Last Version Date 2026-05-13

Entry Detail

PDB ID:

9TNG

Keywords:

SIGNALING PROTEIN

Title:

Crystal Structure of the third PDZ domain of PSD-95 protein E401R mutant

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

0.95 Å

R-Value Free:

0.16

R-Value Work:

0.14

R-Value Observed:

0.14

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Disks large homolog 4
Gene (Uniprot):DLG4
Mutagens:E401R
Chain IDs:A
Chain Length:104
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P78352 Pfam ID:PF00595

Ligand Molecules

ACT

Primary Citation

Conformational changes on the third PDZ domain of PSD95 upon phosphorylation of Tyr397.

Salinas-Garcia, M.C, Murciano-Calles, J, Andujar-Sanchez, M, Ortiz-Salmeron, E, Martinez, J.C, Camara-Artigas, A.Show

J.Struct.Biol. 218 108322 108322 (2026)

PMID: 42067080 DOI: 10.1016/j.jsb.2026.108322

Primary Citation of related structures

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