9TNB image
Deposition Date 2025-12-15
Release Date 2026-08-26
Last Version Date 2026-08-26
Entry Detail
PDB ID:
9TNB
Keywords:
MEMBRANE PROTEIN
Title:
GABA-A receptor a3b3g2 + a3NB77 + bicuculline
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Lama glama (Taxon ID: 9844)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.00 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9TNB validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Gamma-aminobutyric acid recep
Chain IDs:A, D
Chain Length:383
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:GABA-A receptor beta-3-bril
Chain IDs:B, E
Chain Length:451
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Gamma-aminobutyric acid recep
Chain IDs:C
Chain Length:371
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:a3NB77
Chain IDs:F, G
Chain Length:124
Number of Molecules:2
Biological Source:Lama glama
Ligand Molecules
H0Z
NAG
Primary Citation
Determining the molecular and physiological actions of subtype-selective nanobodies of GABA A receptors.
Sci Adv 12 eaeg3548 eaeg3548 (2026)
PMID: 42525743 DOI: 10.1126/sciadv.aeg3548
Primary Citation of related structures
9TNB
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