9TMN image
Deposition Date 2025-12-15
Release Date 2026-09-09
Last Version Date 2026-09-23
Entry Detail
PDB ID:
9TMN
Keywords:
Title:
Human sperm 20S proteasome complex isolated from native source
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
Resolution:
1.85 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA6
Chain IDs:A, N (auth: O)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA2
Chain IDs:B, O (auth: P)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA4
Chain IDs:C, P (auth: Q)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Isoform 3 of Proteasome subun
Gene (Uniprot):PSMA8
Chain IDs:D, V (auth: R)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA5
Chain IDs:E, Q (auth: S)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA1
Chain IDs:F, Z (auth: T)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA3
Chain IDs:G, R (auth: U)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB6
Chain IDs:H, S (auth: V)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB7
Chain IDs:I, T (auth: W)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB3
Chain IDs:J, U (auth: X)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB2
Chain IDs:K, AA (auth: Y)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB5
Chain IDs:X (auth: L), DA (auth: Z)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB1
Chain IDs:L (auth: M), Y (auth: a)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB4
Chain IDs:M (auth: N), W (auth: b)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:tripeptide
Chain IDs:BA (auth: d), CA (auth: e)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Molecular architecture and spatial organization of proteasomes in the human sperm nucleus.
Nat.Struct.Mol.Biol. 33 1367 1380 (2026)
PMID: 42680909 DOI: 10.1038/s41594-026-01870-z
Primary Citation of related structures
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