9TLP image
Deposition Date 2025-12-11
Release Date 2026-08-19
Last Version Date 2026-08-19
Entry Detail
PDB ID:
9TLP
Keywords:
Title:
De novo designed single-chain antiparallel coiled-coil hairpin with binding site for BCL-xL, Sc-apCC-2-BCL-xL-6
Biological Source:
Source Organism(s):
Method Details:
Experimental Method:
Resolution:
1.75 Å
R-Value Free:
0.20
R-Value Work:
0.15
R-Value Observed:
0.15
Space Group:
P 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Sc-apCC-2-BCL-xL-6
Chain IDs:A, B, C, D
Chain Length:75
Number of Molecules:4
Biological Source:synthetic construct
Primary Citation
De Novo-Designed Bifunctional
J.Am.Chem.Soc. ? ? ? (2026)
DOI: 10.1021/jacs.6c07593
Primary Citation of related structures
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