9TJY image
Deposition Date 2025-12-08
Release Date 2026-07-01
Last Version Date 2026-07-01
Entry Detail
PDB ID:
9TJY
Keywords:
HYDROLASE
Title:
Crystal Structure of the Human Oncogenic Splice Variant Rac1b Fused with the Scaffold Protein POSH (residues 319-348)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.77 Å
R-Value Free:
0.21
R-Value Work:
0.15
Space Group:
P 21 21 2
9TJY validation report missing
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Isoform B of Ras-related C3 b
Gene (Uniprot):RAC1, SH3RF1
Mutagens:Rac1b Fused to POSH peptide
Chain IDs:A
Chain Length:226
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P63000,Q7Z6J0 Pfam ID:PF00071 EC:3.6.5.2
Ligand Molecules
CL
GNP
MG
POL
Primary Citation
Alternative Splicing of a Structured Partner Alters the Folding-Upon-Binding Trajectory of an Intrinsically Disordered Protein
JACS ? ? ? (2026)
DOI: 10.1021/jacs.6c04072
Primary Citation of related structures
9TJY
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