9TJT image
Deposition Date 2025-12-08
Release Date 2026-08-05
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9TJT
Keywords:
RNA BINDING PROTEIN
Title:
Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole cmpd6 in the pre-activation state
Biological Source:
Source Organism(s):
Escherichia coli (Taxon ID: 562)
Expression System(s):
Escherichia coli, In vitro transcription vector pt7-fluc(deltai)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.87 Å
R-Value Free:
0.24
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 1 21 1
9TJT validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Leucine--tRNA ligase
Gene (Uniprot):leuS
Chain IDs:A
Chain Length:880
Number of Molecules:1
Biological Source:Escherichia coli
UniProt ID:P07813 Pfam ID:PF09334, PF13603, PF00133, PF08264 EC:6.1.1.4
Polymer Type:polyribonucleotide
Molecule:tRNA(leu)
Chain IDs:B
Chain Length:86
Number of Molecules:1
Biological Source:Escherichia coli
Ligand Molecules
EYT
GOL
ZN
Primary Citation
The Zn Domain Acts as a Dynamic Switch Coordinating Multiple-Step Aminoacylation in Bacterial Leucyl-tRNA Synthetase
Nucleic Acids Res. ? ? ? (2026)
DOI: 10.1093/nar/gkag786
Primary Citation of related structures
9TJT
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