ISDA: 9TH8

Deposition Date 2025-12-03

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9TH8

Keywords:

REPLICATION

Title:

Cryo-EM structure of MCM2-7 DH bound to Sld3-Sld7, Cdc45 and DNA

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae (Taxon ID: 4932)

Expression System(s):

Saccharomyces cerevisiae

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM2
Chain IDs:C (auth: B), I (auth: 2)
Chain Length:868
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

UniProt ID:P29469 Pfam ID:PF12619, PF14551, PF17207, PF00493, PF17855 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM3
Chain IDs:D (auth: C), J (auth: 3)
Chain Length:971
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

UniProt ID:P24279 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF22207, PF23191 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM4
Chain IDs:E (auth: D), K (auth: 4)
Chain Length:933
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

UniProt ID:P30665 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF21128 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Minichromosome maintenance pr
Gene (Uniprot):MCM5
Chain IDs:F (auth: E), L (auth: 5)
Chain Length:775
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

UniProt ID:P29496 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF21933 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM6
Chain IDs:G (auth: F), M (auth: 6)
Chain Length:1017
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

UniProt ID:P53091 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF18263 EC:3.6.4.12

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Gene (Uniprot):MCM7
Chain IDs:H (auth: G), N (auth: 7)
Chain Length:845
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

UniProt ID:P38132 Pfam ID:PF14551, PF17207, PF00493, PF17855, PF24901 EC:3.6.4.12

Polymer Type:polydeoxyribonucleotide
Molecule:dsDNA (60-MER)
Chain IDs:A (auth: O)
Chain Length:60
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

Polymer Type:polydeoxyribonucleotide
Molecule:dsDNA (60-MER)
Chain IDs:B (auth: S)
Chain Length:60
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA replication regulator SLD
Gene (Uniprot):SLD3
Chain IDs:O (auth: X)
Chain Length:668
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P53135 Pfam ID:PF18523, PF08639

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Mitochondrial morphogenesis p
Gene (Uniprot):SLD7
Chain IDs:Q (auth: Y)
Chain Length:257
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:Q08457 Pfam ID:PF18636, PF18596

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cell division control protein
Gene (Uniprot):CDC45
Chain IDs:P (auth: Z)
Chain Length:650
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:Q08032 Pfam ID:PF02724

Ligand Molecules