ISDA: 9T94

Deposition Date 2025-11-13

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

9T94

Keywords:

TRANSFERASE

Title:

cryo-EM structure of AKT phosphorylated mTOR complex 2, focused on a single protomer

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Serine/threonine-protein kina
Gene (Uniprot):MTOR
Chain IDs:A
Chain Length:2590
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P42345 Pfam ID:PF11865, PF02259, PF23593, PF08771, PF00454, PF02260

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Target of rapamycin complex s
Gene (Uniprot):MLST8
Chain IDs:B (auth: C)
Chain Length:326
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9BVC4 Pfam ID:PF00400

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Rapamycin-insensitive compani
Gene (Uniprot):RICTOR
Chain IDs:C (auth: E)
Chain Length:1734
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q6R327 Pfam ID:PF14664, PF14666, PF14663, PF14668, PF14665

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Target of rapamycin complex 2
Gene (Uniprot):MAPKAP1
Chain IDs:D (auth: G)
Chain Length:522
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9BPZ7 Pfam ID:PF05422, PF16978, PF25322, PF16979

Modified Residue