ISDA: 9T8E

Deposition Date 2025-11-12

Release Date 2026-07-29

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9T8E

Keywords:

DNA

Title:

Crystal structure of lurbinectedin bound to 10-mer duplex DNA

Biological Source:

Source Organism(s):

DNA molecule (Taxon ID: 2853804)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.30 Å

R-Value Free:

0.21

R-Value Work:

0.20

Space Group:

P 41 3 2

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Macromolecular Entities

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*CP*GP*AP*TP*GP*CP*
Chain IDs:A, B
Chain Length:10
Number of Molecules:2
Biological Source:DNA molecule

Ligand Molecules

A1JUE

SPM

Primary Citation

The structures of ecteinascidins bound to DNA shed light on their mechanism of action

Darriere, T, Ruiz, F.M, Martinez-Diez, M, Lima Ribeiro, M, Cuevas, C, Fernandez-Tornero, C.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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