ISDA: 9T73

Deposition Date 2025-11-10

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9T73

Keywords:

OXIDOREDUCTASE

Title:

Tetrapodal ancestor of L-amino acid oxidase: I224A-Q225H-P361-PREGA-L367 mutant bound to phenylalanine

Biological Source:

Source Organism(s):

Tetrapoda (Taxon ID: 32523)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.82 Å

R-Value Free:

0.27

R-Value Work:

0.19

R-Value Observed:

0.20

Space Group:

P 1 21 1

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Tetrapodal ancestor of L-amin
Chain IDs:A (auth: B), B (auth: A), C, D
Chain Length:485
Number of Molecules:4
Biological Source:Tetrapoda

Ligand Molecules

FAD

PHE

Primary Citation

Evolution of Human IL4i1 Preference for Aromatic Amino Acids from a Broad-Specificity L-Amino Acid Oxidase Ancestor

Massari, M, Caroli, J, Malatesta, M, Marchese, S, Sente, F, Pizzorni, L, Mattevi, A.Show

PNAS ? ? ? (2026)

Primary Citation of related structures

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