9T5P image
Deposition Date 2025-11-05
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
9T5P
Keywords:
MEMBRANE PROTEIN
Title:
Structure of heteromeric mouse LRRC8A/D Volume-Regulated Anion Channel in complex with synthetic nanobody Sb4
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Homo sapiens, Escherichia coli mc1061
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.97 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9T5P validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Volume-regulated anion channe
Chain IDs:A, B, C, D
Chain Length:806
Number of Molecules:4
Biological Source:Mus musculus
Polymer Type:polypeptide(L)
Molecule:Volume-regulated anion channe
Chain IDs:E, F
Chain Length:458
Number of Molecules:2
Biological Source:Mus musculus
Polymer Type:polypeptide(L)
Molecule:Volume-regulated anion channe
Chain IDs:G (auth: J)
Chain Length:128
Number of Molecules:1
Biological Source:Mus musculus
Ligand Molecules
EDO
Primary Citation
Structures of the volume-regulated anion channel LRRC8A/D in activating and inhibiting conditions
To Be Published ? ? ? (?)
Primary Citation of related structures
9T5P
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