9T5H image
Deposition Date 2025-11-05
Release Date 2026-07-15
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9T5H
Keywords:
TRANSCRIPTION
Title:
RNA polymerase II bound to Gdown1 and RPAP2
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.70 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9T5H validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Chain IDs:A
Chain Length:1970
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:A0AAG2TJB2 EC:2.7.7.6
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):POLR2B
Chain IDs:B
Chain Length:1174
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P30876 Pfam ID:PF04563, PF04561, PF04565, PF04566, PF04567, PF00562, PF04560 EC:2.7.7.6,3.1.13.-,2.7.7.48
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):POLR2C
Chain IDs:C
Chain Length:275
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P19387 Pfam ID:PF01193, PF01000
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):POLR2D
Chain IDs:D
Chain Length:142
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O15514 Pfam ID:PF03874
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):POLR2E
Chain IDs:E
Chain Length:210
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P19388 Pfam ID:PF03871, PF01191
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):POLR2F
Chain IDs:F
Chain Length:127
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P61218 Pfam ID:PF01192
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):POLR2G
Chain IDs:G
Chain Length:172
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62487 Pfam ID:PF03876, PF00575
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):POLR2H
Chain IDs:H
Chain Length:150
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P52434 Pfam ID:PF03870
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):POLR2I
Chain IDs:I
Chain Length:125
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P36954 Pfam ID:PF02150, PF01096
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):POLR2L
Chain IDs:J
Chain Length:67
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62875 Pfam ID:PF01194
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):POLR2J
Chain IDs:K
Chain Length:117
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P52435 Pfam ID:PF13656
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):POLR2K
Chain IDs:L
Chain Length:58
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P53803 Pfam ID:PF03604
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):POLR2M
Chain IDs:M
Chain Length:368
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P0CAP2 Pfam ID:PF15328
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Putative RNA polymerase II su
Gene (Uniprot):RPAP2
Chain IDs:N
Chain Length:612
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8IXW5 Pfam ID:PF04181 EC:3.1.3.16
Ligand Molecules
ZN
Primary Citation
Structure of cytoplasmic RNA polymerase II.
Nat Commun ? ? ? (2026)
PMID: 42443208 DOI: 10.1038/s41467-026-75416-8
Primary Citation of related structures
9T5H
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