ISDA: 9T4T

Deposition Date 2025-10-31

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

9T4T

Keywords:

CELL CYCLE

Title:

Structure of Centrosomin (Cnn) partial PReM domain 490-579 WT of Drosophila melanogaster

Biological Source:

Source Organism(s):

Drosophila melanogaster (Taxon ID: 7227)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.04 Å

R-Value Free:

0.23

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 61

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Centrosomin
Gene (Uniprot):cnn
Chain IDs:A, B
Chain Length:92
Number of Molecules:2
Biological Source:Drosophila melanogaster

UniProt ID:P54623

Ligand Molecules

PO4

Primary Citation

Polo/PLK1 phosphorylation relieves Centrosomin/Cnn autoinhibition to promote centrosome scaffold assembly.

Mohamad, N, Wong, S.S, Majumdar, A, Wainman, A, Holland-Kaye, I, Hubatsch, L, Novak, Z, Pozniakovsky, A, Ruer-Gruss, M, Haensele, A.F.M, Caballe, A, Johnson, S, Lea, S.M, Hyman, A.A, Raff, J.W.Show

Embo J. ? ? ? (2026)

PMID: 42533085 DOI: 10.1038/s44318-026-00878-x

Primary Citation of related structures

Feedback Form