9T46 image
Deposition Date 2025-10-30
Release Date 2026-05-13
Last Version Date 2026-05-13
Entry Detail
PDB ID:
9T46
Keywords:
Title:
Crystal structure of the Fab 40G5c in complex with a CD3 epsilon peptide
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
1.65 Å
R-Value Free:
0.22
R-Value Work:
0.18
R-Value Observed:
0.18
Space Group:
P 21 21 21
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin Fab fragment 4
Chain IDs:A (auth: H)
Chain Length:224
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin Fab fragment 4
Chain IDs:B (auth: L)
Chain Length:219
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:T-cell surface glycoprotein C
Gene (Uniprot):CD3E
Chain IDs:C (auth: P)
Chain Length:10
Number of Molecules:1
Biological Source:Homo sapiens
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PCA C GLN modified residue
Primary Citation
Engineering of acidic pH-responsive anti-CD3 binding antibodies.
Mabs 18 2658902 2658902 (2026)
PMID: 42046367 DOI: 10.1080/19420862.2026.2658902
Primary Citation of related structures
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