ISDA: 9T2A

Deposition Date 2025-10-22

Release Date 2026-09-30

Last Version Date 2026-09-30

Entry Detail

PDB ID:

9T2A

Keywords:

IMMUNE SYSTEM

Title:

Human Single Domain TCR-like Antibody 6K23 in complex with NY-ESO-1(C165V):HLA-A0201

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.04 Å

R-Value Free:

0.26

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:MHC class I antigen
Gene (Uniprot):HLA-A
Chain IDs:A
Chain Length:276
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:A5I8L1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Gene (Uniprot):B2M
Chain IDs:B
Chain Length:100
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P61769 Pfam ID:PF07654

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cancer/testis antigen 1
Gene (Uniprot):CTAG1A, CTAG1B
Chain IDs:C
Chain Length:9
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P78358

Polymer Type:polypeptide(L)
Molecule:6K23 single-domain antibody
Chain IDs:D
Chain Length:149
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

PEG

Primary Citation

Single-domain TCR-like antibody 6K23 makes an intimate contact with the NY-ESO-1 peptide

Cmunt, D, Didelot, G, Rachid, L, de Tiani, M, Coukos, G, Dunn, S.M.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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