ISDA: 9T1L

Deposition Date 2025-10-21

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9T1L

Keywords:

OXIDOREDUCTASE

Title:

Tetrapodal ancestor of L-amino acid oxidases: W377I mutant bound to phenylalanine

Biological Source:

Source Organism(s):

Tetrapoda (Taxon ID: 32523)

Expression System(s):

Escherichia coli bl21

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.84 Å

R-Value Free:

0.25

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 21 21 21

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Tetrapodal ancestor of L-amin
Chain IDs:A, B
Chain Length:488
Number of Molecules:2
Biological Source:Tetrapoda

Ligand Molecules

FAD

GOL

PEG

PHE

Primary Citation

Evolution of Human IL4i1 Preference for Aromatic Amino Acids from a Broad-Specificity L-Amino Acid Oxidase Ancestor

Massari, M, Caroli, J, Malatesta, M, Marchese, S, Sente, F, Pizzorni, L, Mattevi, A.Show

PNAS ? ? ? (2026)

Primary Citation of related structures

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