ISDA: 9T06

Deposition Date 2025-10-16

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

9T06

Keywords:

HYDROLASE

Title:

Crystal structure of OXA-244 beta-lactamase K73A mutant

Biological Source:

Source Organism(s):

Klebsiella pneumoniae (Taxon ID: 573)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.85 Å

R-Value Free:

0.21

R-Value Work:

0.19

R-Value Observed:

0.20

Space Group:

P 43 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-lactamase
Gene (Uniprot):blaOXA-244
Mutagens:K73A
Chain IDs:A, B
Chain Length:254
Number of Molecules:2
Biological Source:Klebsiella pneumoniae

UniProt ID:L7UXE1

Ligand Molecules

GOL

SO4

Primary Citation

Improved hydrolysis of piperacillin by R214G OXA-48-like variants, a selective advantage under piperacillin-tazobactam exposure

Nermont, R, Oueslati, S, Aumont-Nicaise, M, Retailleau, P, Iorga, B.I, Naas, T.Show

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Primary Citation of related structures

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