ISDA: 9SXE

Deposition Date 2025-10-09

Release Date 2026-10-21

Last Version Date 2026-10-21

Entry Detail

PDB ID:

9SXE

Keywords:

TRANSFERASE

Title:

c-KIT kinase domain in complex with AZD7762

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.33 Å

R-Value Free:

0.26

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Mast/stem cell growth factor
Gene (Uniprot):KIT
Chain IDs:A, B (auth: C)
Chain Length:327
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P10721 EC:2.7.10.1

Ligand Molecules

YDJ

Primary Citation

c-KIT kinase domain in complex with AZD7762

Muehlenberg, T, Teuber, A, Kleinboelting, S.B, Mueller, M.P, Rauh, D.Show

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Primary Citation of related structures

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