ISDA: 9SWR

Deposition Date 2025-10-07

Release Date 2026-05-27

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9SWR

Keywords:

IMMUNE SYSTEM

Title:

Stimulator of interferon genes protein mutant - W119K M120K

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.86 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Stimulator of interferon gene
Gene (Uniprot):STING1
Chain IDs:A, B, C, D, E, F
Chain Length:379
Number of Molecules:6
Biological Source:Homo sapiens

UniProt ID:Q86WV6 Pfam ID:PF23417, PF15009

Ligand Molecules

Primary Citation

The mutational landscape of STING-induced immunity.

Zhang, B, Xu, P, Meng, Y, Gallay, L, Lestelle, F, Morel, H, Fremond, M.L, Correia, B.E, Ablasser, A.Show

Nature ? ? ? (2026)

PMID: 42343134 DOI: 10.1038/s41586-026-10685-3

Primary Citation of related structures

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