9SQQ image
Deposition Date 2025-09-23
Release Date 2026-07-29
Last Version Date 2026-07-29
Entry Detail
PDB ID:
9SQQ
Keywords:
LYASE
Title:
Structure of trans-basal conformer of wild-type human CBS enzyme in absence of substrate and allosteric activators- by Helical approach
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.00 Å
Aggregation State:
FILAMENT
Reconstruction Method:
HELICAL
9SQQ validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cystathionine beta-synthase
Gene (Uniprot):CBS
Chain IDs:A, B, C (auth: E), D (auth: F), E (auth: C), F (auth: D), G, H, I, J
Chain Length:507
Number of Molecules:10
Biological Source:Homo sapiens
UniProt ID:P35520 Pfam ID:PF00291, PF00571 EC:4.2.1.22
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
LLP A LYS modified residue
Ligand Molecules
HEM
Primary Citation
Structural basis for a filamentous morpheein model of human cystathionine beta-synthase
Nat Commun ? ? ? (2026)
DOI: 10.1038/s41467-026-73198-7
Primary Citation of related structures
9SQQ
Feedback Form
Name
Email
Institute
Feedback