9SQ7 image
Deposition Date 2025-09-19
Release Date 2026-07-22
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9SQ7
Keywords:
TRANSFERASE
Title:
Crystal structure of Aurora-A bound to DBS2
Biological Source:
Source Organism(s):
synthetic construct (Taxon ID: 32630)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Synthetic construct, Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.90 Å
R-Value Free:
0.24
R-Value Work:
0.20
Space Group:
P 32 2 1
9SQ7 validation report missing
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DBS2
Chain IDs:A, C
Chain Length:80
Number of Molecules:2
Biological Source:synthetic construct
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Aurora kinase A
Gene (Uniprot):AURKA
Chain IDs:B, D
Chain Length:285
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:O14965 Pfam ID:PF00069 EC:2.7.11.1
Ligand Molecules
ADP
MG
Primary Citation
Selective miniprotein inhibitors of Aurora-A kinase designed using interaction-motif scaffolding
Biorxiv ? ? ? (2026)
DOI: 10.64898/2026.07.12.737516
Primary Citation of related structures
9SQ7
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