9SN0 image
Deposition Date 2025-09-09
Release Date 2026-07-15
Last Version Date 2026-07-15
Entry Detail
PDB ID:
9SN0
Keywords:
TRANSFERASE
Title:
TKD of human Muscle Specific Kinase (MuSK)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.20 Å
R-Value Free:
0.23
R-Value Work:
0.21
Space Group:
I 4
9SN0 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Muscle, skeletal receptor tyr
Gene (Uniprot):MUSK
Chain IDs:A
Chain Length:351
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O15146 Pfam ID:PF07714 EC:2.7.10.1
Ligand Molecules
NA
SCN
Primary Citation
An S752D activation loop mutation dynamically primes Muscle-Specific Kinase for activation.
Biochem.J. 483 1221 1235 (2026)
PMID: 42240394 DOI: 10.1042/BCJ20260159
Primary Citation of related structures
9SN0
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