ISDA: 9SL1

Deposition Date 2025-09-02

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

9SL1

Keywords:

MEMBRANE PROTEIN

Title:

GABA-A a4b3d receptor in complex with GABA, Nb24 and Mb30

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Escherichia coli (Taxon ID: 562)
Lama glama (Taxon ID: 9844)

Expression System(s):

Homo sapiens, Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.68 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Gamma-aminobutyric acid recep
Mutagens:M120T
Chain IDs:A, C
Chain Length:364
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Gamma-aminobutyric acid recep
Chain IDs:B, D
Chain Length:451
Number of Molecules:2
Biological Source:Homo sapiens, Escherichia coli

Polymer Type:polypeptide(L)
Molecule:GABA-A receptor SBP-delta-glv
Chain IDs:E
Chain Length:430
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Megabody Mb30
Chain IDs:F, H
Chain Length:138
Number of Molecules:2
Biological Source:Lama glama

Polymer Type:polypeptide(L)
Molecule:Nanobody Nb24
Chain IDs:G, I
Chain Length:133
Number of Molecules:2
Biological Source:Lama glama

Ligand Molecules