ISDA: 9SIG

Deposition Date 2025-08-28

Release Date 2026-05-13

Last Version Date 2026-05-13

Entry Detail

PDB ID:

9SIG

Keywords:

OXIDOREDUCTASE

Title:

XFEL structure of oxidised Ribonucleotide reductase R2a Y122F mutant from E. coli

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.90 Å

R-Value Free:

0.18

R-Value Work:

0.15

R-Value Observed:

0.15

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ribonucleoside-diphosphate re
Gene (Uniprot):nrdB
Mutagens:Y122F
Chain IDs:A, B
Chain Length:375
Number of Molecules:2
Biological Source:Escherichia coli

UniProt ID:P69924 Pfam ID:PF00268 EC:1.17.4.1

Ligand Molecules

Primary Citation

Tracking the redox reaction of the iron enzyme ribonucleotide reductase using continuous SerialED and SFX

Pacoste, L, Kumar, R, Srinivas, V, Makita, H, Simon, P.S, Bannerjee, R, Minnetian, N.M, Bhowmick, A, Paley, D.W, Mittan-Moreau, D.W, Chatterjee, K, Rosenberg, D.J, Batyuk, A, Gee, L.B, Alonso-Mori, R, Sauter, N.K, Yano, J, Yachandra, V.K, John, J, Aurelius, O, Brewster, A.S, Kern, J.F, Blomberg, B, Lebrette, H, Xu, H, Hofer, G, Hogbom, M, Zou, X.Show

Structure ? ? ? (2026)

DOI: 10.1016/j.str.2026.03.006

Primary Citation of related structures

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