ISDA: 9SH6

Deposition Date 2025-08-25

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

9SH6

Keywords:

MEMBRANE PROTEIN

Title:

Structure of a GPCR dimer bound to two G proteins

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae (Taxon ID: 4932)

Expression System(s):

Trichoplusia ni, Saccharomyces cerevisiae, Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.77 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Pheromone alpha factor recept
Chain IDs:A (auth: B), B (auth: A)
Chain Length:430
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:F (auth: C), H (auth: F)
Chain Length:423
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:G (auth: E), I (auth: D)
Chain Length:472
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Mutagens:C106S,C107S
Chain IDs:E (auth: G), J (auth: H)
Chain Length:110
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

Polymer Type:polypeptide(L)
Molecule:Mating factor alpha
Chain IDs:C (auth: K), D (auth: I)
Chain Length:13
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae

Ligand Molecules