ISDA: 9SE8

Deposition Date 2025-08-15

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9SE8

Keywords:

TRANSFERASE

Title:

Crystal structure of ULK1 in complex with inhibitor SBP-5147

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.22

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 43 21 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Serine/threonine-protein kina
Gene (Uniprot):ULK1
Chain IDs:A, B
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O75385 Pfam ID:PF00069 EC:2.7.11.1

Modified Residue

Compound ID	Chain ID	Parent Comp ID	Details	2D Image
TPO	A	THR	modified residue

Ligand Molecules

A1JNH

EDO

GOL

SO4

Primary Citation

Crystal structure of ULK1 in complex with inhibitor SBP-5147

Chaikuad, A, Layng, F.I.A.L, Ren, H, Cosford, N.D.P, Knapp, S, Structural Genomics Consortium (SGC)Show

to be published ? ? ? (?)

Primary Citation of related structures

Feedback Form