ISDA: 9S9E

Deposition Date 2025-08-06

Release Date 2026-09-02

Last Version Date 2026-09-02

Entry Detail

PDB ID:

9S9E

Keywords:

ANTITOXIN

Title:

Co-crystal of broadly neutralizing biparatopic monomeric VHH in complex with cardiotoxin (P01468) naja pallida

Biological Source:

Source Organism(s):

Vicugna pacos (Taxon ID: 30538)
Naja pallida (Taxon ID: 8658)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.31 Å

R-Value Free:

0.21

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 2 2 21

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Variable Domain of Heavy-Chai
Chain IDs:A, B
Chain Length:125
Number of Molecules:2
Biological Source:Vicugna pacos

Polymer Type:polypeptide(L)
Molecule:Cytotoxin 1
Chain IDs:C, D
Chain Length:60
Number of Molecules:2
Biological Source:Naja pallida

Ligand Molecules

ACT

Primary Citation

Structural and functional characterization of a biparatopic monomeric nanobody

Burlet, N.J, Yildirim, E.B, Tomberli, I, Bertelsen, A.B, Ahmadi, S, Ljungars, A, Laustsen, A.H, Morth, J.P.Show

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Primary Citation of related structures

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