ISDA: 9S95

Deposition Date 2025-08-06

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

9S95

Keywords:

TRANSPORT PROTEIN

Title:

Strucutre of human transthyretin mutant I68L bound to tafamidis

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.55 Å

R-Value Free:

0.22

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 21 21 2

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Transthyretin
Mutagens:I68L
Chain IDs:A, B
Chain Length:115
Number of Molecules:2
Biological Source:Homo sapiens

Ligand Molecules

3MI

Primary Citation

Strucutre of human transthyretin mutant I68L buond to tafamidis

Calderone, V, Fragai, M, Cerofolini, L, Russomanno, P, Callozzo, S.Show

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Primary Citation of related structures

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